| août 202509 août |  Championship | QPR 1–1 PrestonRegular Season - 1 | N |
| 12 août |  EFL Cup | Barrow 0–1Preston1st Round | V |
| 16 août | Championship | Preston2–1 LeicesterRegular Season - 2 | V |
| 23 août | Championship | Preston1–0 IpswichRegular Season - 3 | V |
| 26 août | EFL Cup | Preston2–3 Wrexham2nd Round | D |
| 30 août | Championship | Portsmouth 1–0PrestonRegular Season - 4 | D |
| septembre 202513 sept. | Championship | Preston2–2 MiddlesbroughRegular Season - 5 | N |
| 20 sept. | Championship | Derby 0–1PrestonRegular Season - 6 | V |
| 27 sept. | Championship | Preston0–0 Bristol CityRegular Season - 7 | N |
| 30 sept. | Championship | Hull City 2–2PrestonRegular Season - 8 | N |
| octobre 202504 oct. | Championship | Preston2–0 CharltonRegular Season - 9 | V |
| 18 oct. | Championship | West Brom 2–1PrestonRegular Season - 10 | D |
| 21 oct. | Championship | Preston0–1 BirminghamRegular Season - 11 | D |
| 24 oct. | Championship | Preston3–2 Sheffield UtdRegular Season - 12 | V |
| novembre 202501 nov. | Championship | Southampton 0–2PrestonRegular Season - 13 | V |
| 05 nov. | Championship | Preston2–1 SwanseaRegular Season - 14 | V |
| 08 nov. | Championship | Millwall 1–1PrestonRegular Season - 15 | N |
| 21 nov. | Championship | Preston1–2 BlackburnRegular Season - 16 | D |
| 25 nov. | Championship | Watford 1–1PrestonRegular Season - 17 | N |
| 29 nov. | Championship | Sheffield Wednesday 2–3PrestonRegular Season - 18 | V |
| décembre 202506 déc. | Championship | Preston1–1WrexhamRegular Season - 19 | N |
| 09 déc. | Championship | Preston1–1 CoventryRegular Season - 20 | N |
| 13 déc. | Championship | Oxford United 1–2PrestonRegular Season - 21 | V |
| 20 déc. | Championship | Preston1–1 NorwichRegular Season - 22 | N |
| 26 déc. | Championship | Stoke City 0–0PrestonRegular Season - 23 | N |
| 29 déc. | Championship | Wrexham2–1PrestonRegular Season - 24 | D |
| janvier 202601 janv. | Championship | Preston3–0Sheffield WednesdayRegular Season - 25 | V |
| 04 janv. | Championship | Bristol City0–2PrestonRegular Season - 26 | V |
| 09 janv. |  FA Cup | Preston0–1 WiganRound of 64 | D |
| 17 janv. | Championship | Preston0–1DerbyRegular Season - 27 | D |
| 20 janv. | Championship | Preston0–3Hull CityRegular Season - 28 | D |
| 24 janv. | Championship | Middlesbrough4–0PrestonRegular Season - 29 | D |
| 31 janv. | Championship | Ipswich1–1PrestonRegular Season - 30 | N |
| février 202607 févr. | Championship | Preston1–0PortsmouthRegular Season - 31 | V |
| 14 févr. | Championship | Preston2–2WatfordRegular Season - 32 | N |
| 20 févr. | Championship | Blackburn1–0PrestonRegular Season - 33 | D |
| 24 févr. | Championship | Swansea1–1PrestonRegular Season - 34 | N |
| 28 févr. | Championship | Preston0–2MillwallRegular Season - 35 | D |
| mars 202606 mars | Championship | Preston1–3Oxford UnitedRegular Season - 36 | D |
| 11 mars | Championship | Coventry3–0PrestonRegular Season - 37 | D |
| 14 mars | Championship | Norwich2–0PrestonRegular Season - 38 | D |
| 20 mars | Championship | Preston3–1Stoke CityRegular Season - 39 | V |
| avril 202603 avr. | Championship | Leicester2–2PrestonRegular Season - 40 | N |
| 06 avr. | Championship | Preston1–1QPRRegular Season - 41 | N |
| 11 avr. | Championship | Charlton1–2PrestonRegular Season - 42 | V |
| 18 avr. | Championship | Preston0–2West BromRegular Season - 43 | D |
| 22 avr. | Championship | Birmingham2–1PrestonRegular Season - 44 | D |
| 25 avr. | Championship | Sheffield Utd2–3PrestonRegular Season - 45 | V |
| mai 202602 mai | Championship | Preston1–3SouthamptonRegular Season - 46 | D |
