| juliol del 202623 de jul. |  Europa League | Twente 1–2 Ferencvarosi TC2nd Qualifying Round | D |
| 30 de jul. | Europa League | Ferencvarosi TC20:30Twente2nd Qualifying Round | — |
| agost del 202609 d’ag. |  Eredivisie | Heerenveen 16:45TwenteRegular Season - 1 | — |
| 16 d’ag. | Eredivisie | Twente14:30 PEC ZwolleRegular Season - 2 | — |
| 30 d’ag. | Eredivisie | Cambuur 20:00TwenteRegular Season - 4 | — |
| setembre del 202606 de set. | Eredivisie | Groningen 12:15TwenteRegular Season - 5 | — |
| 09 de set. | Eredivisie | Twente18:45 TelstarRegular Season - 3 | — |
| 12 de set. | Eredivisie | Twente16:30 ADO Den HaagRegular Season - 6 | — |
| 20 de set. | Eredivisie | Twente16:45 PSV EindhovenRegular Season - 7 | — |
| octubre del 202610 d’oct. | Eredivisie | Fortuna Sittard 21:00TwenteRegular Season - 8 | — |
| 18 d’oct. | Eredivisie | Twente14:30 UtrechtRegular Season - 9 | — |
| 25 d’oct. | Eredivisie | AZ Alkmaar 20:00TwenteRegular Season - 10 | — |
| novembre del 202601 de nov. | Eredivisie | Excelsior 14:30TwenteRegular Season - 11 | — |
| 08 de nov. | Eredivisie | Twente14:30 AjaxRegular Season - 12 | — |
| 22 de nov. | Eredivisie | Twente17:00 Willem IIRegular Season - 13 | — |
| 29 de nov. | Eredivisie | NEC Nijmegen 17:00TwenteRegular Season - 14 | — |
| desembre del 202606 de des. | Eredivisie | GO Ahead Eagles 17:00TwenteRegular Season - 15 | — |
| 13 de des. | Eredivisie | Twente17:00 Sparta RotterdamRegular Season - 16 | — |
| 20 de des. | Eredivisie | Feyenoord 17:00TwenteRegular Season - 17 | — |
| gener del 202708 de gen. | Eredivisie | Twente20:00Fortuna SittardRegular Season - 18 | — |
| 17 de gen. | Eredivisie | Utrecht17:00TwenteRegular Season - 19 | — |
| 24 de gen. | Eredivisie | Twente17:00HeerenveenRegular Season - 20 | — |
| 31 de gen. | Eredivisie | Twente17:00CambuurRegular Season - 21 | — |
| febrer del 202714 de febr. | Eredivisie | PSV Eindhoven17:00TwenteRegular Season - 22 | — |
| 21 de febr. | Eredivisie | Twente17:00ExcelsiorRegular Season - 23 | — |
| 28 de febr. | Eredivisie | ADO Den Haag17:00TwenteRegular Season - 24 | — |
| març del 202707 de març | Eredivisie | Twente17:00AZ AlkmaarRegular Season - 25 | — |
| 14 de març | Eredivisie | Willem II17:00TwenteRegular Season - 26 | — |
| 21 de març | Eredivisie | Twente17:00GO Ahead EaglesRegular Season - 27 | — |
| abril del 202704 d’abr. | Eredivisie | Ajax17:00TwenteRegular Season - 28 | — |
| 11 d’abr. | Eredivisie | Telstar17:00TwenteRegular Season - 29 | — |
| 25 d’abr. | Eredivisie | Twente17:00NEC NijmegenRegular Season - 30 | — |
| maig del 202702 de maig | Eredivisie | Sparta Rotterdam17:00TwenteRegular Season - 31 | — |
| 09 de maig | Eredivisie | Twente17:00GroningenRegular Season - 32 | — |
| 16 de maig | Eredivisie | Twente14:30FeyenoordRegular Season - 33 | — |
| 23 de maig | Eredivisie | PEC Zwolle14:30TwenteRegular Season - 34 | — |
